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HIV Cure?

hivinfectedcell.jpg
Could HIV’s days be numbered? If new research pans out, yes.

Some crafty German scientists managed to craft an enzyme that cuts HIV DNA from infected cells, according to a report in Science. The enzyme, Tre recombinase, took only three months to successfully destroy HIV living in human tissue – in a laboratory, of course.

Such an enzyme could potentially provide a cure. Alan Engelman of Harvard’s Dana-Farber Cancer Institute writes, “A customized enzyme that effectively excises integrated HIV-1 from infected cells in vitro might one day help to eradicate (the) virus from AIDS patients.”

Though promising, the enzyme does not guarantee the end of HIV’s reign of terror.

Sharon Lewin – infectious disease director at Australia’s The Alfred hospital – tells The Australian, “It’s the beginning of a new avenue that we might have towards a cure, but any cure is still a long way off” One of the main problems stems from HIV’s ability to replicate. The Australian continues:

Steve Wesselingh, an HIV physician and director of Melbourne’s Burnet Institute, said it was an important step as eradication had been considered practically impossible.

“There’s a huge number of cells that have integrated viral DNA, including brain cells,” Professor Wesselingh said. “You have to design something that can find all the viral DNA and remove it all — all you have to do is leave one copy, and it reactivates.”

Cutting HIV out of infected cells had been dismissed as a distant dream because the virus is so good at hiding itself. As a retrovirus, HIV splices itself into the host cell’s DNA — meaning it is inextricably linked to the person it has infected.

The infected cell can remain in a latent state, when it is all but undetectable by the body’s defence mechanisms, or it can become active. When activated, the infected cell turns into a factory for making more viral copies, killing the cell in the process. The new copies go out to infect other cells.

Antiretroviral drugs can stop replication, but cannot effectively destroy the HIV. Let’s hope that the next few years of research can do something with Tre recombinase.

Let’s also hope some marketing wiz comes up with a more peppy name. “Fucking miracle,” perhaps?

By:           Andrew Belonksy
On:           Jun 29, 2007
Tagged: , , , , ,
  • 7 Comments
    • dumbassdoctors
      dumbassdoctors

      All reports are hype and suck…dream on.

      Nov 5, 2007 at 8:34 pm · @ReplyReply to this comment ·
    • ANGEL
      ANGEL

      I BELIEVE THAT A VACCINE AS WELL AS A CURE IS JUST ON THE HORIZON AND NOTHING CAN STOP IT!
      GOD IS GOOD!

      Dec 2, 2007 at 9:03 am · @ReplyReply to this comment ·
    • God Justice
      God Justice

      You think God is good is a great comment think about the innocent people that were infected because their wife or husband didnt tell or didnt know… it is not God’s intent to kill innocent people this is a sickness like diabetes and cancer and all others without a cure… I am infected an my wife too and we are expecting a baby and I pray to God everyday and we were innocent my ex-girlfriend didnt tell me anything and I never thought she would date other men. This is a horrible thing I just hope someone finds the cure…

      Dec 18, 2007 at 5:37 pm · @ReplyReply to this comment ·
    • ktwpsjf iwkfgmlco
      ktwpsjf iwkfgmlco

      tfhqewl cqoekm sglpmz migas ocsmh kxujyqfc sdzaouvbm

      Sep 6, 2008 at 7:19 pm · @ReplyReply to this comment ·
    • ishmael mbendera
      ishmael mbendera

      Everything is possible in the name of God and hope one day vaccine for HIV will be found.

      Mar 18, 2009 at 3:35 am · @ReplyReply to this comment ·
    • Keorapetse seepamedi
      Keorapetse seepamedi

      I would like to regularly get info on new developments

      Jun 13, 2009 at 4:26 am · @ReplyReply to this comment ·
    • mariakatrina
      mariakatrina

      Hi, I work in a communication company I want to share my testimony to
      the world, my name is maria Katrina, i am from united kingdom in
      Belfast north Ireland, I was a stripper in a club I got effected with
      HIV due to the nature of my job, In April 15 2013 i was tested
      positive to HIV, This is not design to convince you but its just a
      personal health experience . I never taught doctor Hakim could ever
      get my HIV-AIDS cured with his healing herb spell, i have tried almost
      everything but I couldn’t find any solution on my disease, despite all
      these happening to me, i always spend a lot to buy a HIV drugs from
      hospital and taking some several medications but no relieve, until one
      day i was just browsing on the internet when i came across a great
      post of !Michelle! who truly said that she was been diagnose with HIV
      and was healed that very week through the help of this great powerful
      healing spell doctor ,I wonder why he is called the great papa Hakim,
      i never knew it was all because of the great and perfect work that he
      has been doing that is causing all this. so I quickly contacted him,
      and he ask me some few questions and so i did all the things he asked
      me to do,He ask me to buy some herbs and which I did for my cure,only
      to see that at the very day which he said i will be healed, all the
      strength that has left me before rush back and i becomes very strong
      and healthy, this disease almost kills my life all because of me, so i
      went to hospital to give the final test to the disease and the doctor
      said i am HIV negative, i am very amazed and happy about the healing
      doctor Hakim gave to me from the ancient part of Africa, you can email
      him now for your own healing too on his email:
      dr.hakimherbalspellworld@gmail.com

      Jan 7, 2014 at 9:45 pm · @ReplyReply to this comment ·

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